Applying for ethical approval
There are different pathways to approval depending on where your research is being carried out, whether the research is low risk or high risk, and who is conducting the research.
Approval pathway diagrams
Category A projects
Externally funded project involving human participants (not NHS patients) (students and staff)
Category B projects
Externally/internally funded project involving human participants (NHS patients) (students and staff)
Category C projects
Externally/internally funded project using human tissue as defined by the Human Tissue Act 2004
Category D projects
Internally funded project involving human participants (not NHS patients)
The research ethics review process via the university or Faculty research ethics committees.
Completing an ethics application
You should aim to prepare ethics applications early, as the processes and procedures of scrutiny can take up to six weeks to complete.
Human participant research
Please complete the
application form and ensure you read the guidance in the
form. Please consider carefully any ethical issues relating to
Applications should provide sufficient information for a decision to be reached by the Committee.
Human tissue research
All research using human tissue requires ethical approval.
Human tissue is defined as material that has come from a human body
and consists of, or includes, human cells.
See the Policies and Procedures for the University's policy relating to research using human tissue and the operating procedures related to the ethical review, oversight and management of human tissue research.
Research with ethical issues but not involving human participants
Research which does not involve human participants but which is high risk or has potential for negative impacts on the environment or society may be submitted for review by a UWE research ethics committee.
You can apply using the application form (research not involving human participants). Please ensure you read the guidance in the form and consider carefully any ethical issues relating to your research.
Applications for approval by FREC/UREC
On receipt of a valid completed application form and all supporting documentation the FREC or UREC officer will register the application. The application is scrutinised by members of the Committee, who decide whether or not to approve the application, and where necessary, seek further information from the applicant. In exceptional circumstances a FREC may refer the application to the UREC for review. The approval process may take up to six weeks or longer over the summer vacation.
Application outcome and feedback
Applicants will be notified and generally feedback from the UREC or FREC will be made available. Applicants are encouraged to regard the comments and feedback from a research ethics committee as helpful and to respond constructively, especially where further work is required for the Committee to be able to reach a favourable decision.
If your project is research, and involves NHS patients, service users, organs, tissue, data or other bodily material, or is to be conducted on NHS property you may need NHS Research Ethics (REC) approval. Please note, this will be in addition to, and in advance of, the University's research ethics approval but will not normally require two separate applications.
Details on how to apply to the NHS REC are available on the NHS Health Research authority website. If you are unsure as to whether you require NHS REC approval, please refer to the approval guidance available on the Health Research Authority website.
Some projects in social care settings may be submitted to the National Social Care Research Ethics Committee.
Once ethical approval has been given by FREC/UREC, the researcher is required to notify the Research Ethics Committee, in advance, of any proposed significant amendment to the original protocol (for example changes to the study population, revised methodology) using the official amendment form. The Committee may then wish to review its opinion.
Further advice and guidance
For further advice on how to seek research ethics approval for your project, students should consult their supervisor, and staff may contact a member of their Faculty Research Ethics Committee. See further information on guidance and support.