Projects in the Centre for Research in Biosciences
Researchers in the centre have secured funding for projects that have resulted in real scientific, social and economic benefits.
We are currently undertaking a range of projects.
Read more about the differences some of our projects are making
Dr Tim Craig at UWE Bristol is looking into novel mechanisms involved in the pathology of type-II diabetes and the regulation of blood glucose levels.
Researchers from CRIB are currently working as part of the Southeast Asia Rainforest Research Partnership (SEARRP) to investigate the environmental impacts of oil palm expansion. The aim is to improve the understanding of rainforest conversion to oil palm and to develop new strategies to improve the sustainability of the industry.
Dr Gabrielle Wheway from UWE's Centre for Research in Biosciences has been awarded funding from the Wellcome Trust and National Eye Research Centre (NERC) to investigate a specific group of proteins which are mutated in retinitis pigmentosa, the most common cause of inherited blindness.
Dr Michael Ladomery from UWE's Centre for Research in Biosciences is currently developing splice switching oligonucleotides (SSOs) targeted against the ERG oncogene, and oncogene that is activated in a staggering proportion (~50%) of prostate cancers.
Dr Jason Mansell from UWE's Centre for Research in Biosciences is currently developing superior, multi-functional bone biomaterials for orthopaedic and dental applications.
Researchers from CRIB are part of a consortium investigating the movement and effects radioactivity in the environment. The aim is to improve significantly predictions of radionuclide behaviour so that safety assessments have a secure scientific basis. The consortium is part of the NERC Radioactivity and The Terrestrial Environment (RATE) programme.
Researchers from the Department of Applied Sciences are working to produce a device that can confirm the presence of disease by smell, with a £1.3 million award from the Wellcome Trust.
Researchers from the Centre for Research in Biosciences are working with the charity BRACE on a project that may lead to earlier interventions that slow or even prevent progression of Alzheimer’s Disease.
Working with industry colleagues, researchers from the centre have developed screen-printed amperometric biosensors that could lead to a rapid test for toxic organophosphate pesticides in food and water supplies.
UWE Bristol (Professor Dawn Arnold) has teamed up with the Universities of Oxford (Dr Gail Preston) and Reading (Dr Robert Jackson) to win a £500,000 grant to study ways of increasing crop yields by reducing disease. The award from the Biotechnologies and Biological Sciences Research Council (BBSRC) enables researchers to build on recent discoveries about how disease spreads in bean plants. The 3-year project could result in developing new ways to prevent diseases in this valuable food crop.
Native oak species in Britain are being attacked by a disorder known as Acute Oak Decline (AOD). UWE scientists, Dr Carrie Brady and Professor Dawn Arnold, are now working in collaboration with Dr Sandra Denman of the Centre for Forestry and Climate Change and the charity Woodland Heritage to investigate the causes of this devastating disease.
The SIMS project is an European Commission FP7 collaboration on the development of a Smart Integrated Miniaturised Sensor (SIMS) system using integrated organic and printed electronics technologies. Partners to this €2.95M project, which is led by UWE, include Dublin City University, University of Liverpool, Fraunhofer ENAS, VTT and Alere. This technology integrates printed sensors, displays, batteries and organic circuits into a single, disposable device.
Currently, the project has developed an operational prototype capable of measuring cholesterol and which can be used in conjunction with mobile phone technology to transmit the test result to a remote location, allowing effective healthcare management.
For more information on this project and it's partners please see the latest news release.
The SIMS project is also featured in the latest edition of International Innovation which is a print and online journal for dissemination of science and technology research and development.