Bristol Genomics Research Institute (BGRI)
The UWE, Bristol Genomics Research Institute is a major addition to the University, housing state of the art technologies for post-genomics research. Current research is focused mainly on molecular plant science and molecular biomedicine. Recent research conducted in the BGRI include an EU Framework V funded project to develop a new methodology for blood grouping; an EU Framework VI network of excellence funded project to end invasive procedures in prenatal diagnostics; and BBSRC and Defra funded projects to look at 'Oxidative stress' in plants and how plants regulate water loss.
Branching off of OM are 0M006 (the mass spectrometry room); 0M007 (the PCR - Polymerase Chain Reaction - room where DNA is multiplied); and 0M008 (the Proteomics clean room where proteomics (the analysis of proteins from DNA) and transcriptomics (the analysis of DNA) take place.
The BGRI has:
- A core DNA sequencing facility and operates a Applied Biosystem Genetic Analyser 3130xl DNA sequencer
- Two micromass mass spectrometers
- A Bio-Rad Icycler real-time PCR to detect a variety of fluorescent labelled PCR products
- An arrayer and scanner - to be exact a biorobotics microgrid II TAS arrayer that can fabricate DNA protein arrays to a very high density
- In the proteomics/transcriptomics clean room there is a typhoon gel imager to detect proteins on high resolution 1D and 2D cells.
- An Applied Biosystems 7000 realtime PCR machine.