Microbiology and Molecular Biology laboratory

Key facilities

  • PCR and gene cloning
  • Tissue cultures
  • Automated luminescence/fluorescence plate readers
  • Spiral plater and a plate reader for automated determination of bacterial count
  • Chemostats for continuous culturing of aerobic and anaerobic bacteria to study the growth physiology of oral bacteria such as Streptococcus mutans and the effect of antimicrobials.

Applications

  • Oral microbiology: the study of bacteria associated with oral environment and the ecology of the tongue flora.
  • Bioluminescence: The use of bacterial luciferase technology as a sensitive and real-time whole cell reporter in medical, food and environmental applications. Examples of current research include the use of bioluminescence to study the effect of antibiotics and anticancer drugs, the effect of heat treatment on food surfaces, the translocation of pathogenic bacteria across the blood brain barrier, and biofilm community of Pseudomonas aeruginosa.

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